Toole started his professional acting career in London, and then from Edinburgh spent most of his acting career in London's West End. Besides this he toured America as well as Australia and New Zealand. Right now I want to explore his London exposure, which is undoubtedly where he has his major stage success.
Theatres in Victorian London: "Thus ended the memorable history of a playhouse whose stage had seen such nineteenth-century London theatre notables as Hayden Coffin, Henry Irving, Madge Robertson, Fred Lesley, Charles Danby, John Laurence Toole."
He was into the London Theatre scene so much that in the end he took over a theatre and had it named after him! You can read more about this in the Toole's Theatre posting.